Fail:Dna-SNP.svg
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Fail asli (Fail SVG, ukuran dasar 520 × 333 piksel, saiz fail: 1.15 MB)
Fail ini dari Wikimedia Commons dan mungkin digunakan oleh projek lain. Penerangan pada laman penerangan failnya di sana ditunjukkan di bawah.
Ringkasan
| KeteranganDna-SNP.svg |
English: A Single Nucleotide Polymorphism is a change of a nucleotide at a single base-pair location on DNA. Created using OpenSCAD v2021.01 and Inkscape v1.0.2. |
| Tarikh | |
| Sumber | Karya sendiri |
| Pengarang | David Eccles (Gringer) |
Construction process
This file was derived from a 3D model of DNA, converted to SVG and coloured using David Eccles' STL2SVG script:
type=orig; ~/scripts/stl2svg.pl ./DNA_linear_complete_helix1.stl:330 ./DNA_linear_complete_helix2.stl:200 ./DNA_linear_complete_${type}_A.stl:140 ./DNA_linear_complete_${type}_C.stl:250 ./DNA_linear_complete_${type}_G.stl:90 ./DNA_linear_complete_${type}_T.stl:30 > out_${type}.svg
type=mut; ~/scripts/stl2svg.pl ./DNA_linear_complete_helix1.stl:330 ./DNA_linear_complete_helix2.stl:200 ./DNA_linear_complete_${type}_A.stl:140 ./DNA_linear_complete_${type}_C.stl:250 ./DNA_linear_complete_${type}_G.stl:90 ./DNA_linear_complete_${type}_T.stl:30 > out_${type}.svg
The DNA models were then combined and annotated using Inkscape. The DNA backbone for the model is a pentagon extruded over a sine wave using David Eccles' guided path extrude script. The model source file (in OpenSCAD format) is shown below:
use <guided_extrude.scad>;
hl = 100; // helix length
hp = 33.2; // helix pitch [in angstroms]
hr = 10; // helix radius [in angstroms]
bbr = 1.5; // backbone radius
loops = hl / hp;
// random bases
//bases = rands(0, 4, ceil(360 * loops / 34.3),1);
// *GRINGENE* -- TAA GGN MGN ATH AAY GGN GAR AAY GAR TGA
// -- TAA GGC AGG ATC AAC GGC GAG AAC GAG TGA
// A = 0; G = 1; C = 2; T = 3
// [different from my usual order,
// to simplify the 3D model logic]
bases = [3,3,3, 1,1,2, 0,1,1, 0,3,2, 0,0,2,
1,1,2, 1,0,1, 0,0,2, 1,0,1, 3,1,0];
bAng = atan2(sin(120) - sin(0), cos(120) - cos(0));
drawMode = "all";
module lineTo(x1, x2){
hull(){
translate(x1) sphere(r=0.25, $fn=5);
translate(x2) sphere(r=0.25, $fn=5);
}
}
backbone_profile = [for(th = [0:72:359]) [bbr*cos(th),
bbr*sin(th)*1]];
inc = floor($t * 30);
thf = ($t * 30) - inc;
h1limit = (360 * loops);
h1jump = (360 * loops);
helix_1 = [for(th = [(thf*34.3):(34.3/2):h1jump])
[hr * cos(th), hr * sin(th), hl * th / (360 * loops)]];
helix_2 = [for(th = [120:(34.3/2):(360 * loops+120)])
[hr * cos(th), hr * sin(th), hl * (th-120) / (360 * loops)]];
module purine(){
linear_extrude(height=0.75, center=true){
// average hydrogen bond length in water: 1.97 A
// https://en.wikipedia.org/wiki/Hydrogen_bond#Structural_details
translate([-0.985,0])
// scale: average of C-C and C=C bond length
scale(1.435) translate([-2,0]) rotate(12) rotate(18){
rotate(-30) translate([1,0]) circle(r=1, $fn=6);
color("blue")
rotate(36) translate([-1 / (2*sin(36)),0])
circle(r=1 / (2*sin(36)), $fn=5);
}
}
}
module pyrimidine(){
linear_extrude(height=0.75, center=true){
// average hydrogen bond length in water: 1.97 A
// https://en.wikipedia.org/wiki/Hydrogen_bond#Structural_details
translate([-0.985,0])
scale(1.435) translate([-2, 0]) translate([1,0])
circle(r=1, $fn=6);
}
}
$vpt = [0, 0, 0];
//$vpr = [310, 105, 10];
$vpr = [0, 0, 0];
rotate([310, 105, 130]) translate([0,0,-hl/2]) {
if(drawMode == "all" || drawMode == "helix1") color("lightblue")
mapExtrude("vertCylinder", backbone_profile, helix_1);
if(drawMode == "all" || drawMode == "helix2") color("pink")
mapExtrude("vertCylinder", backbone_profile, helix_2);
for(thb = [inc:(360 * loops / 34.3 + inc)]) {
thi = thb-inc;
th = (thi-thf) * 34.3;
thisBase = bases[floor(thb%30)];
doPur = (thisBase < 2);
// base bond has a -1.2° angle;
// not quite sure how to implement that
baseFrac = (doPur ? 0.55 : 0.45);
baseFInv = 1 - baseFrac;
translate([0,0,hl * th / (360 * loops)]) rotate([-1.2,0,0]){
if(drawMode == "all" || drawMode == "helix2") color("pink")
lineTo([hr * cos(th)*(baseFrac-0.15) +
hr * cos(th+120) * (baseFrac+0.15),
hr * sin(th)*(baseFrac-0.15) +
hr * sin(th+120) * (baseFrac+0.15)],
[hr * cos(th+120), hr * sin(th+120)]);
if(th < (h1jump))
if(drawMode == "all" || drawMode == "helix1") color("lightblue")
lineTo([hr * cos(th), hr * sin(th)],
[hr * cos(th)*(baseFrac+0.15) +
hr * cos(th+120) * (baseFrac-0.15),
hr * sin(th)*(baseFrac+0.15) +
hr * sin(th+120) * (baseFrac-0.15)]);
if(drawMode == "all" ||
(drawMode == "A" && thisBase == 0) ||
(drawMode == "G" && thisBase == 1) ||
(drawMode == "C" && thisBase == 2) ||
(drawMode == "T" && thisBase == 3)
)
color((thisBase < 1) ? "green" :
(thisBase < 2) ? "gold" :
(thisBase < 3) ? "blue" :
"red")
translate([hr * cos(th)*baseFrac + hr * cos(th+120) * baseFInv,
hr * sin(th)*baseFrac + hr * sin(th+120) * baseFInv])
rotate(180 + bAng + th) if(doPur) {
purine(); } else { pyrimidine(); };
if(drawMode == "all" ||
(drawMode == "A" && thisBase == 3) ||
(drawMode == "G" && thisBase == 2) ||
(drawMode == "C" && thisBase == 1) ||
(drawMode == "T" && thisBase == 0)
)
if(th < (h1jump))
color((thisBase < 1) ? "red" :
(thisBase < 2) ? "blue" :
(thisBase < 3) ? "gold" :
"green")
translate([hr * cos(th)*baseFrac + hr * cos(th+120) * baseFInv,
hr * sin(th)*baseFrac + hr * sin(th+120) * baseFInv])
rotate(bAng+th) if(doPur) {
pyrimidine(); } else { purine(); };
}
}
if(drawMode == "all" || drawMode == "helix1") color("lightblue") {
translate(helix_1[len(helix_1)-1]) sphere(r=bbr, $fn=5);
translate(helix_1[0]) sphere(r=bbr, $fn=5);
}
if(drawMode == "all" || drawMode == "helix2") color("pink") {
translate(helix_2[0]) sphere(r=bbr, $fn=5);
translate(helix_2[len(helix_2)-1]) sphere(r=bbr, $fn=5);
}
}
Perlesenan
Dengan ini, saya selaku pemegang hak cipta karya ini, menerbitkannya di bawah lesen-lesen yang berikut:
| Kebenaran diberikan untuk menyalin, mengedar dan/atau mengubah dokumen ini di bawah syarat-syarat Lesen Pendokumenan Bebas GNU, versi 1.2 atau mana-mana versi selepas ini, yang diterbitkan oleh Yayasan Perisian Bebas; tanpa Seksyen yang Tak Berubah, tanpa Teks Kulit Depan dan tanpa Teks Kulit Belakang. Salinan lesen ini boleh didapati dalam seksyen yang bertajuk Lesen Pendokumenan Bebas GNU".http://www.gnu.org/copyleft/fdl.htmlGFDLGNU Free Documentation Licensetruetrue |
Fail ini dilesenkan di bawah lesen Pengiktirafan 4.0 Antarabangsa Creative Commons.
Pengiktirafan:
SNP model by David Eccles (gringer)
- Anda bebas:
- untuk berkongsi – untuk menyalin, mengedar dan memindah hasil kerja
- untuk mencampur semula – untuk menyesuaikan karya
- Di bawah syarat berikut:
- pengiktirafan – Anda mesti memberi penghargaan yang berpatutan, bekalkan pautan ke lesen, dan tunjukkan jika perubahan telah dibuat. Anda boleh lakukannya dalam sebarang cara yang munasabah, tetapi bukan dalam sebarang cara yang mencadangkan pemberi lesen mengendors anda atau penggunaan anda.
Anda boleh memilih mana-mana lesen yang anda mahukan.
Captions
Add a one-line explanation of what this file represents
DNA sequence variation in a population. A SNP is just a single nucleotide difference in the genome. The upper DNA molecule differs from the lower DNA molecule at a single base-pair location (a G/A polymorphism)
Items portrayed in this file
menggambarkan
18 Disember 2014
media type Inggeris
image/svg+xml
1,203,312 bait
333 piksel
520 piksel
80e2618911371d2da8252d8edc5d36cf8c929c94
Sejarah fail
Klik pada tarikh/waktu untuk melihat rupa fail tersebut pada waktu itu.
| Tarikh/Waktu | Gambar kenit | Ukuran | Pengguna | Komen | |
|---|---|---|---|---|---|
| semasa | 14:07, 8 Mei 2021 | 520 × 333 (1.15 MB) | wikimediacommons>Gringer | Update to slightly more accurate 3D model, showing base rings |
Penggunaan fail
Laman berikut menggunakan fail ini:
Diambil daripada "https://ms.wiki.beta.math.wmflabs.org/wiki/Fail:Dna-SNP.svg"